TargetMol

(S)-Baclofen

Product Code:
 
TAR-T20962
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20962-5mg5mg£850.00
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Quantity:
TAR-T20962-50mg50mg£1,661.00
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Quantity:
TAR-T20962-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
(S)-Baclofen has effects on excitation in the ascending auditory pathway leading to it a potential reagent for the treatment of hyperactive auditory disorders such as hyperacusis and tinnitus.
CAS:
66514-99-6
Formula:
C10H12ClNO2
Molecular Weight:
213.66
Purity:
0.98
SMILES:
NC[C@@H](CC(O)=O)c1ccc(Cl)cc1

References

1. Zheng Y, McPherson K, Smith PF. Effects of early and late treatment with L-baclofen on the development and maintenance of tinnitus caused by acoustic trauma in rats. Neuroscience. 2014 Jan 31;258:410-21. doi: 10.1016/j.neuroscience.2013.11.032. Epub 2013 Nov 26. PubMed PMID: 24291770. 2. Zheng Y, Vagal S, McNamara E, Darlington CL, Smith PF. A dose-response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats. Neuropharmacology. 2012 Feb;62(2):940-6. doi: 10.1016/j.neuropharm.2011.09.027. Epub 2011 Oct 12. PubMed PMID: 22005094. 3. Fromm GH, Terrence CF. Comparison of L-baclofen and racemic baclofen in trigeminal neuralgia. Neurology. 1987 Nov;37(11):1725-8. PubMed PMID: 3313099. 4. Olpe HR, Demi?ville H, Baltzer V, Bencze WL, Koella WP, Wolf P, Haas HL. The biological activity of d- and l-baclofen (Lioresal). Eur J Pharmacol. 1978 Nov 1;52(1):133-6. PubMed PMID: 214308.