TargetMol

Peramivir

Product Code:
 
TAR-T21339
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21339-5mg5mg£850.00
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Further Information

Bioactivity:
Peramivir, a neuraminidase inhibitor, acts as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. It is used as an antiviral drug for the treatment of influenza.
CAS:
330600-85-6
Formula:
C15H28N4O4
Molecular Weight:
328.413
Purity:
0.98
SMILES:
CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@H](C[C@H]1NC(N)=N)C(O)=O

References

1. Peramivir (Rapivab): an IV neuraminidase inhibitor for treatment of influenza. Med Lett Drugs Ther. 2015 Feb 2;57(1461):17-9. PubMed PMID: 25629811. 2. Sato M, Ito M, Suzuki S, Sakuma H, Takeyama A, Oda S, Watanabe M, Hashimoto K, Miyazaki K, Kawasaki Y, Hosoya M. Influenza Viral Load and Peramivir Kinetics after Single Administration and Proposal of Regimens for Peramivir Administration against Resistant Variants. Antimicrob Agents Chemother. 2014 Dec 29. pii: AAC.04263-14. [Epub ahead of print] PubMed PMID: 25547357. 3. Komeda T, Ishii S, Itoh Y, Ariyasu Y, Sanekata M, Yoshikawa T, Shimada J. Post-marketing safety and effectiveness evaluation of the intravenous anti-influenza neuraminidase inhibitor peramivir (II): A pediatric drug use investigation. J Infect Chemother. 2014 Nov 26. pii: S1341-321X(14)00402-4. doi: 10.1016/j.jiac.2014.11.009. [Epub ahead of print] PubMed PMID: 25523716. 4. Hata A, Akashi-Ueda R, Takamatsu K, Matsumura T. Safety and efficacy of peramivir for influenza treatment. Drug Des Devel Ther. 2014 Oct 24;8:2017-38. doi: 10.2147/DDDT.S46654. eCollection 2014. PubMed PMID: 25368514; PubMed Central PMCID: PMC4216046.