TargetMol

Adaptaquin

Product Code:
 
TAR-T22022
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22022-5mg5mg£108.00
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TAR-T22022-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T22022-10mg10mg£135.00
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TAR-T22022-25mg25mg£201.00
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TAR-T22022-50mg50mg£282.00
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TAR-T22022-100mg100mg£402.00
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TAR-T22022-200mg200mg£544.00
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Quantity:
TAR-T22022-500mg500mg£828.00
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This product comes from: United States.
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Further Information

Bioactivity:
Adaptaquin is an inhibitor of the hypoxia-inducing factor prolyl hydroxylase (HIF-PH) [1] [2].
CAS:
385786-48-1
Formula:
C21H16ClN3O2
Molecular Weight:
377.82
Pathway:
Chromatin/Epigenetic; Angiogenesis
Purity:
0.98
SMILES:
Oc1cccnc1NC(c(cc1)ccc1Cl)c(ccc1cccnc11)c1O
Target:
HIF

References

1. Natalya A Smirnova, et, al. Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation. Chem Biol. 2010 Apr 23;17(4):380-91. 2. S Neitemeier, et, al. Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis. Cell Death Dis. 2016 May 5;7(5):e2214.