TargetMol

Antalarmin hydrochloride

Product Code:
 
TAR-T22577
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22577-1mg1mg£103.00
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TAR-T22577-5mg5mg£148.00
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TAR-T22577-10mg10mg£195.00
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TAR-T22577-25mg25mg£322.00
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TAR-T22577-50mg50mg£445.00
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Quantity:
TAR-T22577-100mg100mg£619.00
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This product comes from: United States.
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Further Information

Bioactivity:
Antalarmin hydrochloride is an antagonist of corticotropin-releasing factor 1(CRF1). Antalarmin hydrochloride produces anti-inflammatory effects and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.
CAS:
220953-69-5
Formula:
C24H35ClN4
Molecular Weight:
415.02
Pathway:
Immunology/Inflammation; GPCR/G Protein
Purity:
1
SMILES:
Cl.N=1C(=NC(=C2C1N(C=3C(=CC(=CC3C)C)C)C(=C2C)C)N(CC)CCCC)C
Target:
CRFR; Immunology/Inflammation related

References

1. Zorrilla EP, et al. Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat. Brain Res. 2002 Oct 18;952(2):188-99. 2. Deak T, et al. The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress. Endocrinology. 1999 Jan;140(1):79-86. 3. Webster EL, et al. In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation. Endocrinology. 1996 Dec;137(12):5747-50.