TargetMol

SBE13 Hydrochloride

Product Code:
 
TAR-T2271
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2271-5mg5mg£111.00
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Quantity:
TAR-T2271-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T2271-10mg10mg£136.00
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TAR-T2271-25mg25mg£208.00
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Quantity:
TAR-T2271-50mg50mg£309.00
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Quantity:
TAR-T2271-100mg100mg£433.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
SBE13 hydrochloride is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.
CAS:
1052532-15-6
Formula:
C24H28Cl2N2O4
Molecular Weight:
479.4
Pathway:
Apoptosis; Autophagy; Cell Cycle/Checkpoint
Purity:
0.9901
SMILES:
Cl.COc1ccc(CCNCc2ccc(OCc3ccc(Cl)nc3)c(OC)c2)cc1OC
Target:
Apoptosis; PLK; Autophagy

References

1. Keppner S, et al. Cell Cycle. 2010, 9(4), 761-773. 2. Keppner S, et al. Cell Cycle. 2011, 10(4), 708-720. 3. Lange L, et al. Oncotarget. 2014, 5(8), 2263-2275.