TargetMol

TC-A 2317 hydrochloride

Product Code:
 
TAR-T23426
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23426-5mg5mg£850.00
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TAR-T23426-50mg50mg£1,661.00
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Quantity:
TAR-T23426-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
TC-A 2317 hydrochloride is an inhibitor of Aurora kinase A with a Ki of 1.2 nM compared to Aurora kinase B with a Ki of 101 nM. TC-A 2317 hydrochloride shows antitumor activity.
CAS:
1245907-03-2
Formula:
C19H29ClN6O
Molecular Weight:
392.93
Pathway:
Cell Cycle/Checkpoint; Chromatin/Epigenetic;
Purity:
0.98
SMILES:
Cl.CC(CCCC(C)(C)O)Nc1nc(Nc2cc(C)[nH]n2)cc(C)c1[N+]#[C-]
Target:
Aurora Kinase

References

1. Ando R, et al. 3-Cyano-6-(5-methyl-3-pyrazoloamino)pyridines: selective Aurora A kinase inhibitors. Bioorg Med Chem Lett. 2010;20(15):4709-4711.