TargetMol

Entacapone acid

Product Code:
 
TAR-T24030
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24030-50mg50mgEnquire
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TAR-T24030-5mg5mg£111.00
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TAR-T24030-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T24030-10mg10mg£127.00
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TAR-T24030-25mg25mg£162.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Entacapone is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).
CAS:
160391-70-8
Formula:
C10H6N2O6
Molecular Weight:
250.166
Pathway:
Metabolism
Purity:
0.98
SMILES:
OC(=O)C(=Cc1cc(O)c(O)c(c1)[N+]([O-])=O)C#N
Target:
Transferase

References

1. Belal F, et al. Micellar HPLC-UV method for the simultaneous determination of levodopa, carbidopa and entacapone in pharmaceuticals and human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 May 22;1091:36-45. 2. Engelbrecht I, Petzer JP, Petzer A. Nitrocatechol Derivatives of Chalcone as Inhibitors of Monoamine Oxidase and Catechol-O-Methyltransferase. Cent Nerv Syst Agents Med Chem. 2018 Apr 26. 3. Gr?nig D, et al. Effect of the catechol-O-methyltransferase inhibitors tolcapone and entacapone on fatty acid metabolism in HepaRG cells. Toxicol Sci. 2018 Apr 23. 4. Ware BR, et al. Exploring Chronic Drug Effects on Microengineered Human Liver Cultures Using Global Gene Expression Profiling. Toxicol Sci. 2017 Jun 1;157(2):387-398.