TargetMol

EPZ-025654 HCl

Product Code:
 
TAR-T24037
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24037-5mg5mg£1,332.00
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Quantity:
TAR-T24037-50mg50mg£2,625.00
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Quantity:
TAR-T24037-100mg100mg£3,524.00
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This product comes from: United States.
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Further Information

Bioactivity:
EPZ-025654 is an effective and selective inhibitor of arginine methyltransferase CARM1.
CAS:
1888328-89-9
Formula:
C29H33ClN8O3
Molecular Weight:
577.09
Purity:
0.98
SMILES:
CNC[C@@H](O)COc1ccc(Cl)c(c1)-c1nc(N2Cc3cnc(nc3C2)N2CCC2)c(C)c(n1)-c1c(C)noc1C

References

1. Drew AE, Moradei O, Jacques SL, Rioux N, Boriack-Sjodin AP, Allain C, Scott MP, Jin L, Raimondi A, Handler JL, Ott HM, Kruger RG, McCabe MT, Sneeringer C, Riera T, Shapiro G, Waters NJ, Mitchell LH, Duncan KW, Moyer MP, Copeland RA, Smith J, Chesworth R, Ribich SA. Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma. Sci Rep. 2017 Dec 21;7(1):17993. doi: 10.1038/s41598-017-18446-z. PubMed PMID: 29269946; PubMed Central PMCID: PMC5740082.