TargetMol

EPZ-030456

Product Code:
 
TAR-T24038
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24038-5mg5mg£1,171.00
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Quantity:
TAR-T24038-50mg50mg£2,303.00
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Quantity:
TAR-T24038-100mg100mg£3,042.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
EPZ-030456 is an effective and selective inhibitor of the SMYD3.
CAS:
1808011-23-5
Formula:
C28H34ClN5O4S
Molecular Weight:
572.12
Purity:
0.98
SMILES:
[H][C@]12CC[C@]([H])(C[C@@H](C1)NC(=O)c1cc3CC(=O)Nc3cc1Cl)N2S(=O)(=O)N1CCC(CC1)NCc1ccccc1

References

1. Mitchell LH, Boriack-Sjodin PA, Smith S, Thomenius M, Rioux N, Munchhof M, Mills JE, Klaus C, Totman J, Riera TV, Raimondi A, Jacques SL, West K, Foley M, Waters NJ, Kuntz KW, Wigle TJ, Scott MP, Copeland RA, Smith JJ, Chesworth R. Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor. ACS Med Chem Lett. 2015 Aug 27;7(2):134-8. doi: 10.1021/acsmedchemlett.5b00272. eCollection 2016 Feb 11. PubMed PMID: 26985287; PubMed Central PMCID: PMC4753551.