TargetMol

Ficellomycin

Product Code:
 
TAR-T24063
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24063-5mg5mg£850.00
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Further Information

Bioactivity:
Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.
CAS:
59458-27-4
Formula:
C13H24N6O3
Molecular Weight:
312.374
Purity:
0.98
SMILES:
CC(C)C(N)C(=O)NC(C1CC(N=C(N)N)C2CN12)C(O)=O

References

1. He X, Li M, Song S, Wu X, Zhang J, Wu G, Yue R, Cui H, Song S, Ma C, Lu F, Zhang H. Ficellomycin: an aziridine alkaloid antibiotic with potential therapeutic capacity. Appl Microbiol Biotechnol. 2018 Mar 30. doi: 10.1007/s00253-018-8934-4. [Epub ahead of print] Review. PubMed PMID: 29602982. 2. Liu Y, Li M, Mu H, Song S, Zhang Y, Chen K, He X, Wang H, Dai Y, Lu F, Yan Z, Zhang H. Identification and characterization of the ficellomycin biosynthesis gene cluster from Streptomyces ficellus. Appl Microbiol Biotechnol. 2017 Oct;101(20):7589-7602. doi: 10.1007/s00253-017-8465-4. Epub 2017 Sep 11. PubMed PMID: 28894917. 3. Foulke-Abel J, Agbo H, Zhang H, Mori S, Watanabe CM. Mode of action and biosynthesis of the azabicycle-containing natural products azinomycin and ficellomycin. Nat Prod Rep. 2011 Apr;28(4):693-704. doi: 10.1039/c0np00049c. Epub 2011 Feb 15. Review. PubMed PMID: 21327255. 4. Kuo MS, Yurek DA, Mizsak SA. Structure elucidation of ficellomycin. J Antibiot (Tokyo). 1989 Mar;42(3):357-60. PubMed PMID: 2708128.