TargetMol

L 731734

Product Code:
 
TAR-T24350
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24350-5mg5mg£1,091.00
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Quantity:
TAR-T24350-50mg50mg£2,143.00
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Quantity:
TAR-T24350-100mg100mg£2,801.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
L 731734 is a farnesyltransferase inhibitor.
CAS:
149786-89-0
Formula:
C19H38N4O3S
Molecular Weight:
402.6
Purity:
0.98
SMILES:
CCC(C)C(CN[C@@H]([C@@H](C)CC)C(=O)NC1CCOC1=O)NCC(N)CS

References

1. Kohl NE, Wilson FR, Thomas TJ, Bock RL, Mosser SD, Oliff A, Gibbs JB. Inhibition of Ras function in vitro and in vivo using inhibitors of farnesyl-protein transferase. Methods Enzymol. 1995;255:378-86. PubMed PMID: 8524123. 2. Graham SL, deSolms SJ, Giuliani EA, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Breslin MJ, Deana AA, et al. Pseudopeptide inhibitors of Ras farnesyl-protein transferase. J Med Chem. 1994 Mar 18;37(6):725-32. PubMed PMID: 8145221. 3. Kohl NE, Mosser SD, deSolms SJ, Giuliani EA, Pompliano DL, Graham SL, Smith RL, Scolnick EM, Oliff A, Gibbs JB. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science. 1993 Jun 25;260(5116):1934-7. PubMed PMID: 8316833.