TargetMol

PF-06679142

Product Code:
 
TAR-T24622
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24622-5mg5mg£1,010.00
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Quantity:
TAR-T24622-50mg50mg£1,982.00
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Quantity:
TAR-T24622-100mg100mg£2,560.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.
CAS:
1467059-66-0
Formula:
C20H17F2NO3
Molecular Weight:
357.357
Purity:
0.98
SMILES:
OC(=O)c1c[nH]c2cc(F)c(-c3ccc(cc3)[C@@H]3CCCCO3)c(F)c12

References

1. Edmonds DJ, Kung DW, Kalgutkar AS, et al. Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK). J Med Chem. 2018 Feb 28. doi: 10.1021/acs.jmedchem.7b01641. [Epub ahead of print] PubMed PMID: 29466005.