TargetMol

RS-0466

Product Code:
 
TAR-T24739
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24739-5mg5mg£850.00
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TAR-T24739-50mg50mg£1,661.00
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Quantity:
TAR-T24739-100mg100mg£2,079.00
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  • Further Information
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Further Information

Bioactivity:
RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.
CAS:
536993-37-0
Formula:
C17H17N5O2
Molecular Weight:
323.356
Purity:
0.98
SMILES:
CCc1nc(Nc2cccc(O)c2)nc(Nc2cccc(O)c2)n1

References

1. Kubo T, Nishimura S, Murasugi T, Kaneko I, Meguro M, Marumoto S, Kogen H, Koyama K, Oda T, Nakagami Y. 6-Ethyl-N,N'-bis(3-hydroxyphenyl)[1,3,5]triazine-2,4-diamine (RS-0466) enhances the protective effect of brain-derived neurotrophic factor on amyloid beta-induced cytotoxicity in cortical neurones. Pharmacol Toxicol. 2003 Dec;93(6):264-8. PubMed PMID: 14675459. 2. Nishimura S, Murasugi T, Kubo T, Kaneko I, Meguro M, Marumoto S, Kogen H, Koyama K, Oda T, Nakagami Y. RS-4252 inhibits amyloid beta-induced cytotoxicity in HeLa cells. Pharmacol Toxicol. 2003 Jul;93(1):29-32. PubMed PMID: 12828571. 3. Nakagami Y, Nishimura S, Murasugi T, Kubo T, Kaneko I, Meguro M, Marumoto S, Kogen H, Koyama K, Oda T. A novel compound RS-0466 reverses beta-amyloid-induced cytotoxicity through the Akt signaling pathway in vitro. Eur J Pharmacol. 2002 Dec 13;457(1):11-7. PubMed PMID: 12460638.