TargetMol

TRP-601

Product Code:
 
TAR-T24903
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24903-5mg5mg£850.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
TRP-601 is a caspase inhibitor.
CAS:
1094569-02-4
Formula:
C40H48F2N6O11
Molecular Weight:
826.852
Purity:
0.98
SMILES:
COC(=O)C[C@H](NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N([C@@H](C)C(N)=O)C(CC(=O)OC)C(=O)COc1c(F)cccc1F

References

1. Sifringer M, Bendix I, B?rner C, Endesfelder S, von Haefen C, Kalb A, Holifanjaniaina S, Prager S, Schlager GW, Keller M, Jacotot E, Felderhoff-Mueser U. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis. Cell Death Dis. 2012 Jan 12;3:e250. doi: 10.1038/cddis.2011.133. PubMed PMID: 22237207; PubMed Central PMCID: PMC3270267. 2. Chauvier D, Renolleau S, Holifanjaniaina S, Ankri S, Bezault M, Schwendimann L, Rousset C, Casimir R, Hoebeke J, Smirnova M, Debret G, Trichet AP, Carlsson Y, Wang X, Bernard E, H?bert M, Rauzier JM, Matecki S, Lacampagne A, Rustin P, Mariani J, Hagberg H, Gressens P, Charriaut-Marlangue C, Jacotot E. Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor. Cell Death Dis. 2011 Sep 1;2:e203. doi: 10.1038/cddis.2011.87. PubMed PMID: 21881605; PubMed Central PMCID: PMC3186905.