TargetMol

BCH 2763

Product Code:
 
TAR-T25140
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T25140-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
BCH 2763 is an effective, selective bifunctional thrombin inhibitor that blocks both the anion binding exosite and the active catalytic site.
CAS:
204641-27-0
Formula:
C64H93N11O16
Molecular Weight:
1272.509
Purity:
0.98
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)CCCCN)C(=O)N1CCC[C@H]1C(=O)N([C@@H](CC(C)C)C(O)=O)C(=O)CCCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccccc1

References

1. McClanahan TB, Ignasiak DP, Juneau P, Finkle C, Winocour PD, Gallagher KP. Antithrombotic effects of BCH 2763, a new direct thrombin inhibitor, in a canine model of venous thrombosis. J Thromb Thrombolysis. 1999 Jun;7(3):301-6. PubMed PMID: 10375391. 2. Finkle CD, St Pierre A, Leblond L, Deschenes I, DiMaio J, Winocour PD. BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis--comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban. Thromb Haemost. 1998 Feb;79(2):431-8. PubMed PMID: 9493603. 3. Desch?nes I, Finkle CD, Winocour PD. Effective use of BCH-2763, a new potent injectable direct thrombin inhibitor, in combination with tissue plasminogen activator (tPA) in a rat arterial thrombolysis model. Thromb Haemost. 1998 Jul;80(1):186-91. PubMed PMID: 9684808.