TargetMol

Rilmakalim

Product Code:
 
TAR-T26086
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26086-1mg1mg£175.00
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TAR-T26086-5mg5mg£328.00
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TAR-T26086-10mg10mg£456.00
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TAR-T26086-25mg25mg£702.00
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TAR-T26086-50mg50mg£938.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Rilmakalim is a potassium channel opener that has an antivasoconstrictor effect.
CAS:
132014-21-2
Formula:
C21H23NO5S
Molecular Weight:
401.48
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
CC1(C)Oc2ccc(cc2[C@H]([C@@H]1O)N1CCCC1=O)S(=O)(=O)c1ccccc1
Target:
Sodium Channel

References

1. Wuest M, Kaden S, Hakenberg OW, Wirth MP, Ravens U. Effect of rilmakalim on detrusor contraction in the presence and absence of urothelium. Naunyn Schmiedebergs Arch Pharmacol. 2005 Nov;372(3):203-12. Epub 2005 Nov 11. PubMed PMID: 16283254. 2. Riccioppo Neto F, Mesquita J?nior O, Olivera GB. Antiarrhythmic and electrophysiological effects of the novel KATP channel opener, rilmakalim, in rabbit cardiac cells. Gen Pharmacol. 1997 Aug;29(2):201-5. PubMed PMID: 9251899. 3. Novakovi? A, Gojkovi?-Bukarica L, Beleslin-Coki? B, Japundzi?-Zigon N, Saji? Z, Nezi? D, Peri? M, Djukanovi? B, Kazi? T. Differential antivasoconstrictor effects of levcromakalim and rilmakalim on the isolated human mammary artery and saphenous vein. J Pharmacol Sci. 2003 Jun;92(2):108-14. PubMed PMID: 12832838. 4. Olbrich HG, M?ller M, Lindner S, Henke B, Zarse M, Riehle M, Oremek G, Mutschler E. Glimepiride (Hoe490) inhibits the rilmakalim induced decrease in intracellular free calcium and contraction of isolated heart muscle cells from guinea pigs to a lesser extent than glibenclamide. Int J Cardiol. 1999 Dec 15;72(1):53-63. PubMed PMID: 10636633.