TargetMol

BMT-052

Product Code:
 
TAR-T26871
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
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CodeSizePrice
TAR-T26871-5mg5mg£1,653.00
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TAR-T26871-50mg50mg£3,267.00
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Quantity:
TAR-T26871-100mg100mg£4,488.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).
CAS:
1628720-84-2
Formula:
C30H26F4N6O5
Molecular Weight:
635.624
Purity:
0.98
SMILES:
[2H]C([2H])([2H])Oc1ncc(cc1C(=O)NC(c1ncon1)(C([2H])([2H])[2H])C([2H])([2H])[2H])-c1cc2c(C(=O)NC)c(oc2nc1CCC(F)(F)F)-c1ccc(F)cc1

References

1. Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase Inhibitor Kyle Parcella, Kyle Eastman, Kap-Sun Yeung, Katharine A. Grant-Young, Juliang Zhu, Tao Wang, Zhongxing Zhang, Zhiwei Yin, Dawn Parker, Kathy Mosure, Hua Fang, Ying-Kai Wang, Julie Lemm, Xiaoliang Zhuo, Umesh Hanumegowda, Mengping Liu, Karen Rigat, Maria Donoso, Maria Tuttle, Tatyana Zvyaga, Zuzana Haarhoff, Nicholas A. Meanwell, Matthew G. Soars, Susan B. Roberts, and John F. Kadow Publication Date (Web): June 29, 2017 (Letter) doi: 10.1021/acsmedchemlett.7b00211