TargetMol

CFM-184

Product Code:
 
TAR-T26988
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T26988-100mg100mgEnquire
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Further Information

Bioactivity:
CFM-184 is an orally active factor IXa inhibitor with hFIXa IC50 = 4.9 nM.
CAS:
1819357-88-4
Formula:
C22H20Cl2N8O2
Molecular Weight:
499.36
Purity:
0.98
SMILES:
Cc1ncn(n1)-c1ccc(C(=O)NC2C3CCC2N(C3)c2ncc(Cl)c3c(N)noc23)c(Cl)c1

References

1. Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors In Press, Accepted Manuscript, Available online 6 March 2017 Isao Sakurada, Toshiya Endo, Katsuyoshi Hikita, Tomokazu Hirabayashi, Yoshitaka Hosaka, Yutaka Kato, Yoshitaka Maeda, Shigeki Matsumoto, Takashi Mizuno, Hiroshi Nagasue, Teruyuki Nishimura, Shunsuke Shimada, Mikihiko Shinozaki, Keiko Taguchi, Katsutoshi Takeuchi, Tooru Yokoyama, Alan Hruza, Paul Reichert, Ting Zhang, Harold B. Wood, Kazunari Nakao, et al.