TargetMol

CPUY192018 Disodium

Product Code:
 
TAR-T27077
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
CPUY192018 Disodium is a potent inhibitor of the Keap1-Nrf2 PPI. The inhibition of the Keap1-Nrf2 PPI may be beneficial as a treatment for ulcerative colitis.
CAS:
1567836-15-0
Formula:
C28H24N2Na2O10S2
Molecular Weight:
658.6
Purity:
0.98
SMILES:
[Na+].[Na+].COc1ccc(cc1)S(=O)(=O)N(CC([O-])=O)c1ccc(N(CC([O-])=O)S(=O)(=O)c2ccc(OC)cc2)c2ccccc12

References

1. Lu MC, Ji JA, Jiang YL, Chen ZY, Yuan ZW, You QD, Jiang ZY. An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis. Sci Rep. 2016 May 24;6:26585. doi: 10.1038/srep26585. PubMed PMID: 27215610; PubMed Central PMCID: PMC4877580.