TargetMol

SL327

Product Code:
 
TAR-T2708
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2708-5mg5mg£113.00
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TAR-T2708-10mg10mg£142.00
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TAR-T2708-50mg50mg£308.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.
CAS:
305350-87-2
Formula:
C16H12F3N3S
Molecular Weight:
335.35
Pathway:
DNA Damage/DNA Repair; MAPK; Cell Cycle/Checkpoint
Purity:
0.9974
SMILES:
NC(Sc1ccc(N)cc1)=C(C#N)c1ccccc1C(F)(F)F
Target:
MEK; DNA/RNA Synthesis

References

1. Scherle PA, wt al. J Biol Chem. 2000, 275(47), 37086-37092. 2. Atkins CM, et al. Nat Neurosci, 1998, 1(7), 602-609. 3. Selcher JC, et al. Learn Mem, 1999, 6(5), 478-490. 4. Valjent E, J Neurosci, 2000, 20(23), 8701-8709.