TargetMol

DCYM21

Product Code:
 
TAR-T27134
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27134-5mg5mg£930.00
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Quantity:
TAR-T27134-50mg50mg£1,821.00
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Quantity:
TAR-T27134-100mg100mg£2,319.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DCYM21 is an inhibitor of menin-MLL interaction. DCYM21 demonstrates potent and selective blockage of proliferation and induces both cell cycle arrest and differentiation of leukemia cells harboring MLL translocations.
CAS:
2001072-35-9
Formula:
C26H33ClN2
Molecular Weight:
409.01
Purity:
0.98
SMILES:
NCC(CCN1CCC(=CC1)c1ccc(Cl)cc1)(C1CCCC1)c1ccccc1

References

1. Yue L, Du J, Ye F, Chen Z, Li L, Lian F, Zhang B, Zhang Y, Jiang H, Chen K, Li Y, Zhou B, Zhang N, Yang Y, Luo C. Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide. Org Biomol Chem. 2016 Sep 28;14(36):8503-19. doi: 10.1039/c6ob01248e. Epub 2016 Aug 19. PubMed PMID: 27541268.