TargetMol

Dup-714

Product Code:
 
TAR-T27220
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27220-5mg5mg£1,251.00
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TAR-T27220-50mg50mg£2,464.00
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Quantity:
TAR-T27220-100mg100mg£3,283.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Dup-714 is a thrombin inhibitor.
CAS:
130982-43-3
Formula:
C21H33BN6O5
Molecular Weight:
460.34
Purity:
0.98
SMILES:
CC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)B(O)O

References

1. McBane RD 2nd, Hassinger NL, Mruk JS, Grill DE, Chesebro JH. Direct thrombin inhibitors are not equally effective in vivo against arterial thrombosis: in vivo evaluation of DuP714 and argatroban in a porcine angioplasty model and comparison to r-hirudin. Thromb Res. 2005;116(6):525-32. PubMed PMID: 16181988. 2. De Nanteuil G, Verbeuren TJ. S 18326: a thrombin inhibitor that shows potential for oral treatment of thromboembolic disorders. Expert Opin Investig Drugs. 1999 Feb;8(2):173-80. PubMed PMID: 15992071. 3. Van Aken H, Bode C, Darius H, Diehm C, Encke A, Gulba DC, Haas S, Hacke W, Puhl W, Quante M, Riess H, Scharf R, Schellong S, Schr?r T, Schulte KL, Tebbe U. Anticoagulation: the present and future. Clin Appl Thromb Hemost. 2001 Jul;7(3):195-204. Review. PubMed PMID: 11441979.