TargetMol

Isothiafludine

Product Code:
 
TAR-T27634
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27634-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27634-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27634-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Isothiafludine is a HBV virus inhibitor that dramatically reduces the HBV DNA level in cells.
CAS:
960527-22-4
Formula:
C18H18FN3OS2
Molecular Weight:
375.48
Purity:
0.98
SMILES:
CC(C)Cc1sc(nc1C(=O)NCc1ccc(F)cc1)-c1nccs1

References

1. Yang L, Shi LP, Chen HJ, Tong XK, Wang GF, Zhang YM, Wang WL, Feng CL, He PL, Zhu FH, Hao YH, Wang BJ, Yang DL, Tang W, Nan FJ, Zuo JP. Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation. Acta Pharmacol Sin. 2014 Mar;35(3):410-8. doi: 10.1038/aps.2013.175. PubMed PMID: 24487969; PubMed Central PMCID: PMC4647886. 2. Yang L, Wang YJ, Chen HJ, Shi LP, Tong XK, Zhang YM, Wang GF, Wang WL, Feng CL, He PL, Xu YB, Lu MJ, Tang W, Nan FJ, Zuo JP. Effect of a hepatitis B virus inhibitor, NZ-4, on capsid formation. Antiviral Res. 2016 Jan;125:25-33. doi: 10.1016/j.antiviral.2015.11.004. PubMed PMID: 26611395.