TargetMol

PF-4950834

Product Code:
 
TAR-T28387
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28387-5mg5mg£850.00
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Quantity:
TAR-T28387-50mg50mg£1,661.00
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Quantity:
TAR-T28387-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.
CAS:
1256264-62-6
Formula:
C21H19N3O2
Molecular Weight:
345.402
Purity:
0.98
SMILES:
CNC(=O)c1cccc(CNC(=O)c2ccc(cc2)-c2ccncc2)c1

References

1. Rajagopalan LE, Davies MS, Kahn LE, Kornmeier CM, Shimada H, Steiner TA, Zweifel BS, Wendling JM, Payne MA, Loeffler RF, Case BL, Norton MB, Parikh MD, Nemirovskiy OV, Mourey RJ, Masferrer JL, Misko TP, Kolodziej SA. Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity. J Pharmacol Exp Ther. 2010 Jun;333(3):707-16. doi: 10.1124/jpet.110.166033. Epub 2010 Mar 12. PubMed PMID: 20228155.