TargetMol

Sabeluzole

Product Code:
 
TAR-T28655
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28655-5mg5mg£850.00
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TAR-T28655-50mg50mg£1,661.00
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Quantity:
TAR-T28655-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Sabeluzole is a nootropic and neuroprotective agent. It acts primarily as an NMDA antagonist.
CAS:
104383-17-7
Formula:
C22H26FN3O2S
Molecular Weight:
415.53
Purity:
0.98
SMILES:
OC(COc1ccc(F)cc1)CN1CCC(CC1)NCc1nc2ccccc2s1

References

1. Verreck G, Chun I, Li Y, Kataria R, Zhang Q, Rosenblatt J, Decorte A, Heymans K, Adriaensen J, Bruining M, Van Remoortere M, Borghys H, Meert T, Peeters J, Brewster ME. Preparation and physicochemical characterization of biodegradable nerve guides containing the nerve growth agent sabeluzole. Biomaterials. 2005 Apr;26(11):1307-15. PubMed PMID: 15475061. 2. Pageaux GP, Micallef J, Nataf MB, Levron JC, Lacarelle B, Le Moing JP, Bouhours P, Blin O. Pharmacokinetics of sabeluzole and dextromethorphan oxidation capacity in patients with severe hepatic dysfunction and healthy volunteers. Br J Clin Pharmacol. 2001 Feb;51(2):164-8. PubMed PMID: 11259989; PubMed Central PMCID: PMC2014438. 3. Mohr E, Nair NP, Sampson M, Murtha S, Belanger G, Pappas B, Mendis T. Treatment of Alzheimer's disease with sabeluzole: functional and structural correlates. Clin Neuropharmacol. 1997 Aug;20(4):338-45. PubMed PMID: 9260731. 4. Uberti D, Rizzini C, Galli P, Pizzi M, Grilli M, Lesage A, Spano P, Memo M. Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. Synapse. 1997 Jun;26(2):95-103. PubMed PMID: 9131769.