TargetMol

TLK19781

Product Code:
 
TAR-T28983
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T28983-5mg5mg£850.00
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Further Information

Bioactivity:
TLK19781 is an insulin receptor modulator.
CAS:
309932-60-3
Formula:
C33H24Cl2N4O13S4
Molecular Weight:
883.71
Purity:
0.98
SMILES:
Oc1cc(cc2cc(NC(=O)Nc3ccc4c(O)cc(cc4c3)S(=O)(=O)Nc3ccc(Cl)c(c3)S(O)(=O)=O)ccc12)S(=O)(=O)Nc1ccc(Cl)c(c1)S(O)(=O)=O

References

1. Wu M, Dai G, Yao J, Hoyt S, Wang L, Mu J. Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator. PLoS One. 2015 Mar 23;10(3):e0122012. doi: 10.1371/journal.pone.0122012. eCollection 2015. PubMed PMID: 25799496; PubMed Central PMCID: PMC4370409. 2. Cheng M, Chen S, Schow SR, Manchem VP, Spevak WR, Cristobal CP, Shi S, Macsata RW, Lum RT, Goldfine ID, Keck JG. In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator. J Cell Biochem. 2004 Aug 15;92(6):1234-45. PubMed PMID: 15258906.