TargetMol

BAY8040

Product Code:
 
TAR-T30303
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T30303-5mg5mg£850.00
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Quantity:
TAR-T30303-50mg50mg£1,661.00
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Quantity:
TAR-T30303-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
BAY8040 is a potent selective human neutrophilic elastase inhibitor with excellent potency and selectivity with promising pharmacokinetic characteristics.
CAS:
1194453-23-0
Formula:
C21H16F3N5O2
Molecular Weight:
427.387
Purity:
0.98
SMILES:
CN1CC2=C([C@H](NC(=O)N2c2cccc(c2)C(F)(F)F)c2ccc(cc2)C#N)C(=O)N1

References

1. von Nussbaum F, Li VM, Meibom D, Anlauf S, Bechem M, Delbeck M, Gerisch M, Harrenga A, Karthaus D, Lang D, Lustig K, Mittendorf J, Sch?fer M, Sch?fer S, Schamberger J. Potent and Selective Human Neutrophil Elastase Inhibitors with Novel Equatorial Ring Topology: in vivo Efficacy of the Polar Pyrimidopyridazine BAY-8040 in a Pulmonary Arterial Hypertension Rat Model. ChemMedChem. 2016 Jan;11(2):199-206. doi: 10.1002/cmdc.201500269. Epub 2015 Sep 3. PubMed PMID: 26333652.