TargetMol

CI 922

Product Code:
 
TAR-T30916
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T30916-5mg5mg£1,251.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T30916-50mg50mg£2,464.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T30916-100mg100mg£3,283.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
CI 922 is an anaphylaxis mediator release inhibitor. It inhibits the activation of human neutrophils.
CAS:
97958-08-2
Formula:
C26H30N10O6
Molecular Weight:
578.59
Purity:
0.98
SMILES:
N[C@@H](CCCNC(N)=N)C(O)=O.COc1c(oc2c3cc(OC)ccc3n(-c3ccccc3)c12)C(=O)Nc1nnn[nH]1

References

1. Werns SW, Eller BT, Shea MJ, Simpson PJ, Dysko RC, Abrams GD, Lucchesi BR. Protection of reperfused ischemic canine myocardium by CI-922, a new inhibitor of leukocyte activation. J Cardiovasc Pharmacol. 1988;12(5):608-14. PubMed PMID: 2468062. 2. Wright CD, Hoffman MD, Thueson DO, Conroy MC. Inhibition of human neutrophil activation by the allergic mediator release inhibitor, CI-922: mechanism of inhibitory activity. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1110-7. PubMed PMID: 2825675. 3. Wright CD, Hoffman MD, Thueson DO, Conroy MC. Inhibition of human neutrophil activation by the allergic mediator release inhibitor, CI-922: differential inhibition of responses to a variety of stimuli. J Leukoc Biol. 1987 Jul;42(1):30-5. PubMed PMID: 2439626. 4. Adolphson RL, Finkel MP, Robichaud LJ. CI-922--a novel, potent antiallergic compound--II. Activity in animal models of allergy. Int J Immunopharmacol. 1987;9(1):51-60. PubMed PMID: 2438239.