TargetMol

CS 834

Product Code:
 
TAR-T31106
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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TAR-T31106-5mg5mg£850.00
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Further Information

Bioactivity:
CS 834, a novel oral carbapenem antibiotic, is an ester prodrug of the active metabolite R-95867.
CAS:
157542-49-9
Formula:
C20H28N2O7S
Molecular Weight:
440.51
Purity:
0.98
SMILES:
C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@H]3CNC(=O)C3)=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C

References

1. van Ogtrop ML. CS-834 (Sankyo). IDrugs. 1999 Mar;2(3):254-8. PubMed PMID: 16160937. 2. Kobayashi K, Fukuhara H, Hata T, Ohashi Y. In situ observation of the four-step dehydration process of the 1 beta-methylcarbapenem antibiotic CS-834 crystal by X-rays. Chem Pharm Bull (Tokyo). 2003 Dec;51(12):1356-62. PubMed PMID: 14646309. 3. Kobayashi K, Fukuhara H, Kawamoto I, Hata T, Sekine A, Uekusa H, Ohashi Y. Physicochemical analyses of phase transition and dehydration processes of a new oral 1beta-methylcarbapenem antibiotic agent, CS-834. Chem Pharm Bull (Tokyo). 2002 Dec;50(12):1570-3. PubMed PMID: 12499592. 4. Kobayashi K, Fukuhara H, Kawamoto I, Ito S, Hata T. Crystal structure of a 1beta-methylcarbapenem antibiotic, pivaloyloxymethyl (1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-methyl-2-[[(R)-5-oxopyrrolidin-3-yl]thio]-1-c arbapen-2-em-3-carboxylate, CS-834 dihydrate. Anal Sci. 2001 Feb;17(2):357-8. PubMed PMID: 11990557.