TargetMol

Hgg 12

Product Code:
 
TAR-T32074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32074-5mg5mg£1,167.00
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Further Information

Bioactivity:
Hgg 12 is used to treat organophosphorus poisoning.
CAS:
83972-73-0
Formula:
C20H19Cl2N3O3
Molecular Weight:
420.29
Purity:
0.98
SMILES:
[Cl-].[Cl-].ON=Cc1cccc[n+]1COC[n+]1cccc(c1)C(=O)c1ccccc1

References

1. Hauser W, Weger N. Therapeutic effects of the bis-pyridinium salts HGG-12, HGG-42, and atropine, benactyzine in organophosphate poisoning of dogs. Arch Toxicol Suppl. 1979;(2):393-6. PubMed PMID: 288351. 2. van Helden HP, van der Wiel HJ, Zijlstra JJ, Melchers BP, Busker RW. Comparison of the therapeutic effects and pharmacokinetics of HI-6, HL?-7, HGG-12, HGG-42 and obidoxime following non-reactivatable acetylcholinesterase inhibition in rats. Arch Toxicol. 1994;68(4):224-30. PubMed PMID: 8067894. 3. Cetkovi? S, Cvetkovi? M, Jandri? D, Cosi? M, Boskovi? B. Effect of PAM-2 Cl, HI-6, and HGG-12 in poisoning by tabun and its thiocholine-like analog in the rat. Fundam Appl Toxicol. 1984 Apr;4(2 Pt 2):S116-23. PubMed PMID: 6547103. 4. Boskovi? B, Kovacevi? V, Jovanovi? D. PAM-2 Cl, HI-6, and HGG-12 in soman and tabun poisoning. Fundam Appl Toxicol. 1984 Apr;4(2 Pt 2):S106-15. PubMed PMID: 6724203.