TargetMol

IMC-48

Product Code:
 
TAR-T32146
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32146-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T32146-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T32146-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
IMC-48, as a BCL2 i-motif-interactive compound, can act by stabilizing or facilitating the folding of the i-motif.
CAS:
106068-99-9
Formula:
C35H63IN2O
Molecular Weight:
654.806
Purity:
0.98
SMILES:
[I-].CC(C)CCCC(C)C1CCC2C3CCC4CC(CCC4(C)C3CCC12C)NC(=O)C[N+]1(C)CCCCC1

References

1. Fernandez M, Toimil RF, Rasslan Z, Ilias EJ, Gradinar AL, Malheiros CA. ASSESSMENT OF BODY FAT IN OBESE PATIENTS PREOPERATIVELY FOR BARIATRIC SURGERY. Arq Bras Cir Dig. 2016;29Suppl 1(Suppl 1):59-61. doi: 10.1590/0102-6720201600S10015. English, Portuguese. PubMed PMID: 27683778; PubMed Central PMCID: PMC5064249. 2. Cui Y, Koirala D, Kang H, Dhakal S, Yangyuoru P, Hurley LH, Mao H. Molecular population dynamics of DNA structures in a bcl-2 promoter sequence is regulated by small molecules and the transcription factor hnRNP LL. Nucleic Acids Res. 2014 May;42(9):5755-64. doi: 10.1093/nar/gku185. Epub 2014 Mar 7. PubMed PMID: 24609386; PubMed Central PMCID: PMC4027204. 3. Kang HJ, Kendrick S, Hecht SM, Hurley LH. The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules. J Am Chem Soc. 2014 Mar 19;136(11):4172-85. doi: 10.1021/ja4109352. Epub 2014 Mar 7. PubMed PMID: 24559432; PubMed Central PMCID: PMC3985447.