TargetMol

Lasiocarpine HCl

Product Code:
 
TAR-T32579
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T32579-5mg5mg£850.00
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Further Information

Bioactivity:
Lasiocarpine HCl is a hepatotoxic and carcinogenic food contaminant.
CAS:
1976-49-4
Formula:
C21H35ClNO7
Molecular Weight:
448.96
Purity:
0.98
SMILES:
[ClH-].CO[C@H](C)[C@@](O)(C(=O)OCC1=CC[N@H+]2CC[C@H](OC(=O)C(C)=CC)[C@H]12)C(C)(C)O

References

1. Field RA, Stegelmeier BL, Colegate SM, Brown AW, Green BT. An in vitro comparison of the cytotoxic potential of selected dehydropyrrolizidine alkaloids and some N-oxides. Toxicon. 2015 Apr;97:36-45. doi: 10.1016/j.toxicon.2015.02.001. Epub 2015 Feb 7. PubMed PMID: 25666399. 2. PETERSON JE. EFFECTS OF THE PYRROLIZIDINE ALKALOID, LASIOCARPINE N-OXIDE, ON NUCLEAR AND CELL DIVISION IN THE LIVER RATS. J Pathol Bacteriol. 1965 Jan;89:153-71. PubMed PMID: 14263458. 3. Xia Q, Zhao Y, Von Tungeln LS, Doerge DR, Lin G, Cai L, Fu PP. Pyrrolizidine alkaloid-derived DNA adducts as a common biological biomarker of pyrrolizidine alkaloid-induced tumorigenicity. Chem Res Toxicol. 2013 Sep 16;26(9):1384-96. doi: 10.1021/tx400241c. Epub 2013 Aug 26. PubMed PMID: 23937665. 4. He X, Xia Q, Woodling K, Lin G, Fu PP. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides. J Food Drug Anal. 2017 Oct;25(4):984-991. doi: 10.1016/j.jfda.2017.09.001. Epub 2017 Sep 19. PubMed PMID: 28987376.