TargetMol

Lombricine

Product Code:
 
TAR-T32853
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T32853-5mg5mg£850.00
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TAR-T32853-50mg50mg£1,661.00
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Quantity:
TAR-T32853-100mg100mg£2,079.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Lombricine, as a phosphodiester of 2-guanidinoethanol and D-serine in structure, is a phosphagen that is unique to earthworms.
CAS:
18416-85-8
Formula:
C6H15N4O6P
Molecular Weight:
270.182
Purity:
0.98
SMILES:
N[C@@H](COP(O)(=O)OCCNC(N)=N)C(O)=O

References

1. Doumen C. Variable intron/exon structure in the oligochaete lombricine kinase gene. Gene. 2012 Sep 1;505(2):276-82. doi: 10.1016/j.gene.2012.06.007. Epub 2012 Jun 12. PubMed PMID: 22705027. 2. Bush DJ, Kirillova O, Clark SA, Davulcu O, Fabiola F, Xie Q, Somasundaram T, Ellington WR, Chapman MS. The structure of lombricine kinase: implications for phosphagen kinase conformational changes. J Biol Chem. 2011 Mar 18;286(11):9338-50. doi: 10.1074/jbc.M110.202796. Epub 2011 Jan 6. PubMed PMID: 21212263; PubMed Central PMCID: PMC3058953. 3. Nagasawa H, Sawaki K, Fujii Y, Kobayashi M, Segawa T, Suzuki R, Inatomi H. Inhibition by lombricine from earthworm (Lumbricus terrestris) of the growth of spontaneous mammary tumours in SHN mice. Anticancer Res. 1991 May-Jun;11(3):1061-4. PubMed PMID: 1909513. 4. Ellington WR, Bush J. Cloning and expression of a lombricine kinase from an echiuroid worm: insights into structural correlates of substrate specificity. Biochem Biophys Res Commun. 2002 Mar 8;291(4):939-44. PubMed PMID: 11866456.