Paspaline

Product Code:

TAR-T33887

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T33887-5mg

5mg

£850.00

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Quantity:

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Further Information

Bioactivity:

Paspaline is an indole-diterpene.

CAS:

11024-56-9

Formula:

C28H39NO2

Molecular Weight:

421.625

Purity:

0.98

SMILES:

[H][C@]12Cc3c([nH]c4ccccc34)[C@]1(C)[C@@]1(C)CC[C@]3([H])O[C@@H](CC[C@@]3(C)[C@]1([H])CC2)C(C)(C)O

Documents

References

Sharpe RJ, Johnson JS. Asymmetric Total Synthesis of the Indole Diterpene Alkaloid Paspaline. J Org Chem. 2015 Oct 2;80(19):9740-66. doi: 10.1021/acs.joc.5b01844. PubMed PMID: 26398568; PubMed Central PMCID: PMC4598058. Koz?k L, Szil?gyi Z, T?th L, P?csi I, Moln?r I. Tremorgenic and neurotoxic paspaline-derived indole-diterpenes: biosynthetic diversity, threats and applications. Appl Microbiol Biotechnol. 2019 Feb;103(4):1599-1616. doi: 10.1007/s00253-018-09594-x. Epub 2019 Jan 6. Review. PubMed PMID: 30613899; PubMed Central PMCID: PMC6384164. Saikia S, Parker EJ, Koulman A, Scott B. Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline. FEBS Lett. 2006 Mar 6;580(6):1625-30. Epub 2006 Feb 17. PubMed PMID: 16494875. Sharpe RJ, Johnson JS. A global and local desymmetrization approach to the synthesis of steroidal alkaloids: stereocontrolled total synthesis of paspaline. J Am Chem Soc. 2015 Apr 22;137(15):4968-71. doi: 10.1021/jacs.5b02631. Epub 2015 Apr 9. PubMed PMID: 25856767; PubMed Central PMCID: PMC4409926.