TargetMol

Remikiren

Product Code:
 
TAR-T34285
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34285-5mg5mg£1,332.00
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Quantity:
TAR-T34285-50mg50mg£2,625.00
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Quantity:
TAR-T34285-100mg100mg£3,524.00
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This product comes from: United States.
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Further Information

Bioactivity:
Remikiren is a highly specific renin inhibitor with oral activity for the treatment of hypertensio.
CAS:
126222-34-2
Formula:
C33H50N4O6S
Molecular Weight:
630.85
Purity:
0.98
SMILES:
CC(C)(C)S(=O)(=O)CC(Cc1ccccc1)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC1CCCCC1)C(O)C(O)C1CC1

References

Kleinbloesem CH, Weber C, Fahrner E, Dellenbach M, Welker H, Schr?ter V, Belz GG. Hemodynamics, biochemical effects, and pharmacokinetics of the renin inhibitor remikiren in healthy human subjects. Clin Pharmacol Ther. 1993 May;53(5):585-92. PubMed PMID: 8491068. van Paassen P, de Zeeuw D, Navis G, de Jong PE. Renal and systemic effects of continued treatment with renin inhibitor remikiren in hypertensive patients with normal and impaired renal function. Nephrol Dial Transplant. 2000 May;15(5):637-43. PubMed PMID: 10809804. Himmelmann A, Bergbrant A, Svensson A, Hansson L, Aurell M. Remikiren (Ro 42-5892)--an orally active renin inhibitor in essential hypertension. Effects on blood pressure and the renin-angiotensin-aldosterone system. Am J Hypertens. 1996 Jun;9(6):517-22. PubMed PMID: 8783774. Richter WF, Whitby BR, Chou RC. Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals. Xenobiotica. 1996 Mar;26(3):243-54. PubMed PMID: 8730917.