TargetMol

Taurolithocholic acid

Product Code:
 
TAR-T34788
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T34788-5mg5mg£1,118.00
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Further Information

Bioactivity:
Taurolithocholic acid is a cholagogue and choleretic.
CAS:
516-90-5
Formula:
C26H45NO5S
Molecular Weight:
483.71
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@H](C)CCC(=O)NCCS(O)(=O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C

References

Amonyingcharoen S, Suriyo T, Thiantanawat A, Watcharasit P, Satayavivad J. Taurolithocholic acid promotes intrahepatic cholangiocarcinoma cell growth via muscarinic acetylcholine receptor and EGFR/ERK1/2 signaling pathway. Int J Oncol. 2015;46(6):2317-26. doi: 10.3892/ijo.2015.2939. Epub 2015 Mar 27. PubMed PMID: 25815516; PubMed Central PMCID: PMC4441291. Li Z, Lu M, Chu J, Qiao X, Meng X, Sun B, Zhang W, Xue D. Early proteome analysis of rat pancreatic acinar AR42J cells treated with taurolithocholic acid 3-sulfate. Pancreatology. 2012 May-Jun;12(3):248-56. doi: 10.1016/j.pan.2012.02.006. Epub 2012 Feb 16. PubMed PMID: 22687381. Ma B, Wu L, Lu M, Gao B, Qiao X, Sun B, Xue D, Zhang W. Differentially expressed kinase genes associated with trypsinogen activation in rat pancreatic acinar cells treated with taurolithocholic acid 3-sulfate. Mol Med Rep. 2013 May;7(5):1591-6. doi: 10.3892/mmr.2013.1355. Epub 2013 Mar 4. PubMed PMID: 23467886. Denk GU, Maitz S, Wimmer R, Rust C, Invernizzi P, Ferdinandusse S, Kulik W, Fuchsbichler A, Fickert P, Trauner M, Hofmann AF, Beuers U. Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver. Hepatology. 2010 Nov;52(5):1758-68. doi: 10.1002/hep.23911. PubMed PMID: 21038414.