TargetMol

Way 100135

Product Code:
 
TAR-T35104
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35104-5mg5mg£850.00
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TAR-T35104-50mg50mg£1,661.00
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Quantity:
TAR-T35104-100mg100mg£2,079.00
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Further Information

Bioactivity:
Way 100135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as a potent 5-HT1A receptor antagonist and a partial agonist of the 5-HT1D receptor, and to a much lesser extent, of the 5-HT1B receptor.
CAS:
133025-23-7
Formula:
C24H33N3O2
Molecular Weight:
395.547
Purity:
0.98
SMILES:
COc1ccccc1N1CCN(CC(C(=O)NC(C)(C)C)c2ccccc2)CC1

References

Lopez-Mendoza D, Aguilar-Bravo H, Swanson HH. Combined effects of Gepirone and (+)WAY 100135 on territorial aggression in mice. Pharmacol Biochem Behav. 1998 Sep;61(1):1-8. PubMed PMID: 9715801. Kazmierska P, Konopacki J. Development of theta rhythm in hippocampal formation slices perfused with 5-HT1A antagonist, (S)WAY 100135. Brain Res. 2015 Nov 2;1625:142-50. doi: 10.1016/j.brainres.2015.08.041. Epub 2015 Sep 7. PubMed PMID: 26358147. Wedzony K, Ma?kowiak M, Zajaczkowski W, Fija? K, Chocyk A, Czyrak A. WAY 100135, an antagonist of 5-HT1A serotonin receptors, attenuates psychotomimetic effects of MK-801. Neuropsychopharmacology. 2000 Nov;23(5):547-59. PubMed PMID: 11027920. Nakai K, Fujii T, Fujimoto K, Suzuki T, Kawashima K. Effect of WAY-100135 on the hippocampal acetylcholine release potentiated by 8-OH-DPAT, a serotonin1A receptor agonist, in normal and p-chlorophenylalanine-treated rats as measured by in vivo microdialysis. Neurosci Res. 1998 May;31(1):23-9. PubMed PMID: 9704975.