TargetMol

PROTAC RIPK degrader-6

Product Code:
 
TAR-T36243
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T36243-5mg5mg£457.00
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Quantity:
TAR-T36243-10mg10mg£631.00
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Quantity:
TAR-T36243-1mL1 mL * 10 mM (in DMSO)£689.00
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TAR-T36243-25mg25mg£1,099.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PROTAC RIPK degrader-6 (example 1) is a PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder[1].
CAS:
2089205-64-9
Formula:
C43H48N6O11S2
Molecular Weight:
889
Purity:
0.98
SMILES:
O=S(C(C(OCCOCCOCCOCCOCC(NC1=C(CN(C2C(NC(CC2)=O)=O)C3=O)C3=CC=C1)=O)=C4)=CC(C4=NC=C5)=C5NC6=CC(N=CS7)=C7C=C6)(C(C)(C)C)=O

References

John David Harlin, et al. Compounds for the modulation of rip2 kinase activity. WO2017046036A1.