TargetMol

Bempedoic acid

Product Code:
 
TAR-T3625
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3625-2mg2mg£95.00
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TAR-T3625-5mg5mg£109.00
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TAR-T3625-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T3625-10mg10mg£124.00
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TAR-T3625-25mg25mg£173.00
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TAR-T3625-50mg50mg£254.00
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Quantity:
TAR-T3625-100mg100mg£367.00
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Quantity:
TAR-T3625-500mg500mg£781.00
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This product comes from: United States.
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Further Information

Bioactivity:
ETC-1002, also known as ESP-55016 and Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic acid is absorbed rapidly in the small intestine and enters the liver through cell surface receptors different from those transporters that selectively take up statins. Bempedoic acid is a regulator of lipid and carbohydrate metabolism.
CAS:
738606-46-7
Formula:
C19H36O5
Molecular Weight:
344.492
Pathway:
Metabolism; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Purity:
0.9994
SMILES:
CC(C)(CCCCCC(O)CCCCCC(C)(C)C(O)=O)C(O)=O
Target:
ATP Citrate Lyase; AMPK

References

Nikolic D, et al. Atherosclerosis. 2014, 237(2):705-710. Filippov S, et al. J Lipid Res. 2013, 54(8):2095-2108. Pinkosky SL, et al. J Lipid Res. 2013, 54(1):134-151.