TargetMol

Phosphoramide mustard (cyclohexanamine)

Product Code:
 
TAR-T36701
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36701-5mg5mg£297.00
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Quantity:
TAR-T36701-10mg10mg£470.00
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Further Information

Bioactivity:
Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA adduct formation in ovarian granulosa cells, induces DNA damage and elicits the ovarian DNA repair response[1][2].
CAS:
1566-15-0
Formula:
C10H24Cl2N3O2P
Molecular Weight:
320.2
Purity:
0.98
SMILES:
O=P(N(CCCl)CCCl)(N)O.NC1CCCCC1

References

Shanthi Ganesan, et al. Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells. Toxicol Appl Pharmacol. 2015 Feb 1; 282(3): 252-258. S Genka, et al. Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat. Cancer Chemother Pharmacol. 1990;27(1):1-7.