TargetMol

Vevorisertib

Product Code:
 
TAR-T38847
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38847-5mg5mg£850.00
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Further Information

Bioactivity:
Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor against AKT1 ( IC 50 =0.55 nM), AKT2 ( IC 50 =0.81 nM), and AKT3 ( IC 50 =1.31 nM). Vevorisertib, as a single agent or in combination with other anti-cancer agents, can be used for the research of solid tumors with PIK3CA / AKT / PTEN mutations[4] .
CAS:
1416775-46-6
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Vevorisertib (ARQ 751) (4440-001) as a Single Agent or in Combination With Other Anti-Cancer Agents, in Solid Tumors With PIK3CA / AKT / PTEN Mutations. ArQule Presents Recent Data on ARQ 751 at the 2019 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. Abstract A034: The use of biomarkers and ctDNA in a phase 1 trial of ARQ 751 Abstract 374: In vitro and in vivo anti-tumor activity of ARQ 751, a potent and selective AKT inhibitor