TargetMol

GS-493

Product Code:
 
TAR-T39167
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39167-5mg5mg£850.00
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Further Information

Bioactivity:
GS-493 is a selective protein tyrosine phosphatase SHP2 (PTPN11) inhibitor with an IC 50 of 71 nM. GS-493 is 29- and 45-fold more active toward SHP2 than related SHP1 and PTP1B. GS-493 blocks cellular motility and growth of cancer cells. Antitumor activity.
CAS:
1710337-31-7
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Grosskopf S, et al. Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo. ChemMedChem. 2015;10(5):815-826.