TargetMol

cis-22a

Product Code:
 
TAR-T41233
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T41233-1mg1mg£174.00
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Quantity:
TAR-T41233-5mg5mg£324.00
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TAR-T41233-10mg10mg£540.00
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TAR-T41233-25mg25mg£823.00
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Quantity:
TAR-T41233-50mg50mg£1,091.00
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Quantity:
TAR-T41233-100mg100mg£1,452.00
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Quantity:
TAR-T41233-500mg500mg£2,825.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.
CAS:
1819366-84-1
Formula:
0
Molecular Weight:
0
Pathway:
Membrane transporter/Ion channel|Metabolism
Purity:
0.98
SMILES:
0
Target:
TRP/TRPV Channel|Calcium Channel

References

Humer C, et al. TRPV6 Regulation by Cis-22a and Cholesterol. Biomolecules. 2022;12(6):804. Cunha MR, et al. Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor. RSC Med Chem. 2020;11(9):1032-1040.