TargetMol

Senexin A

Product Code:
 
TAR-T5673
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5673-1mg1mg£111.00
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TAR-T5673-2mg2mg£128.00
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TAR-T5673-1mL1 mL * 10 mM (in DMSO)£161.00
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TAR-T5673-5mg5mg£164.00
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TAR-T5673-10mg10mg£205.00
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TAR-T5673-25mg25mg£334.00
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TAR-T5673-50mg50mg£550.00
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TAR-T5673-100mg100mg£755.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.
CAS:
1366002-50-7
Formula:
C17H14N4
Molecular Weight:
274.327
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
N#Cc1ccc2ncnc(NCCc3ccccc3)c2c1
Target:
CDK

References

Porter D C , Farmaki E , Altilia S , et al. Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities[J]. Proceedings of the National Academy of Sciences, 2012, 109(34):13799-13804.