TargetMol

Amsacrine hydrochloride

Product Code:
 
TAR-T5820
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5820-1mL1 mL * 10 mM (in DMSO)£95.00
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TAR-T5820-10mg10mg£102.00
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TAR-T5820-25mg25mg£117.00
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TAR-T5820-50mg50mg£128.00
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TAR-T5820-100mg100mg£148.00
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TAR-T5820-200mg200mg£177.00
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TAR-T5820-500mg500mg£213.00
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This product comes from: United States.
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Further Information

Bioactivity:
Amsacrine hydrochloride is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.
CAS:
54301-15-4
Formula:
C21H20ClN3O3S
Molecular Weight:
429.92
Pathway:
Autophagy; DNA Damage/DNA Repair
Purity:
0.9971
SMILES:
Cl.COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12
Target:
Topoisomerase; Autophagy

References

Thomas D , Hammerling B C , Wu K , et al. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action[J]. British Journal of Pharmacology, 2004, 142(3):485-494. Attia S M . Molecular cytogenetic evaluation of the mechanism of genotoxic potential of amsacrine and nocodazole in mouse bone marrow cells[J]. Journal of Applied Toxicology, 2013, 33(6).