TargetMol

Tretazicar

Product Code:
 
TAR-T6798
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6798-5mg5mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6798-1mL1 mL * 10 mM (in DMSO)£114.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6798-10mg10mg£130.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6798-25mg25mg£189.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6798-50mg50mg£249.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CB1954(Tretazicar), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.
CAS:
21919-05-1
Formula:
C9H8N4O5
Molecular Weight:
252.186
Pathway:
DNA Damage/DNA Repair
Purity:
0.997
SMILES:
NC(=O)c1cc(N2CC2)c(cc1[N+]([O-])=O)[N+]([O-])=O
Target:
DNA Alkylator/Crosslinker; DNA Alkylation

References

Gui R, et al. Oncol Lett. 2012, 4(3):566-570. Cui W, et al. Gene Ther. 1999, 6(5):764-770. Felmer R, et al. J Endocrinol. 2002, 175(2):487-98.