TargetMol

Deguelin

Product Code:
 
TAR-T6817
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6817-5mg5mg£106.00
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Quantity:
TAR-T6817-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6817-10mg10mg£131.00
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TAR-T6817-25mg25mg£179.00
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TAR-T6817-50mg50mg£280.00
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Quantity:
TAR-T6817-100mg100mg£422.00
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This product comes from: United States.
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Further Information

Bioactivity:
Deguelin is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.
CAS:
522-17-8
Formula:
C23H22O6
Molecular Weight:
394.423
Pathway:
Cytoskeletal Signaling; Autophagy; PI3K/Akt/mTOR signaling; Apoptosis
Purity:
0.9826
SMILES:
COc1cc2OC[C@H]3Oc4c(ccc5OC(C)(C)C=Cc45)C(=O)[C@H]3c2cc1OC
Target:
Apoptosis; Akt; PI3K; Autophagy

References

Liu X, Yang J, Yang C, et al. Morphine promotes the?malignant biological behavior of?non-small cell lung cancer cells through?the?MOR/Src/mTOR pathway. Cancer cell International. 2021, 21(1): 1-14 Wang Y, et al. Mol Clin Oncol. 2013, 1(2):215-219. Bortul R, et al. Br J Haematol. 2005, 129(5):677-86. Liu X, Yang J, Yang C, et al. Morphine promotes the?malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway. Cancer Cell International. 2021, 21(1): 1-14 Yan Y, et al. Neoplasia. 2005, 7(12):1053-7. Kim JH, et al. J Pharmacol Exp Ther. 2008, 324(2):643-7.