TargetMol

SKL2001

Product Code:
 
TAR-T6989
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T6989-5mg5mg£98.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6989-10mg10mg£115.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6989-1mL1 mL * 10 mM (in DMSO)£119.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6989-25mg25mg£158.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6989-50mg50mg£227.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6989-100mg100mg£357.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6989-200mg200mg£502.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6989-500mg500mg£744.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.
CAS:
909089-13-0
Formula:
C14H14N4O3
Molecular Weight:
286.291
Pathway:
Cytoskeletal Signaling; Stem Cells
Purity:
0.9895
SMILES:
O=C(NCCCn1ccnc1)c1cc(on1)-c1ccco1
Target:
Wnt/beta-catenin

References

Lu F, Sun X, Xu X, et al. SILAC-based proteomic profiling of the suppression of TGF-?1-induced lung fibroblast-to-myofibroblast differentiation by trehalose[J]. Toxicology and Applied Pharmacology. 2020: 114916. Lu F, Sun X, Xu X, et al. SILAC-based proteomic profiling of the suppression of TGF-?1-induced lung fibroblast-to-myofibroblast differentiation by trehalose. Toxicology and Applied Pharmacology. 2020: 114916 Lu F, Sun X, Xu X, et al. SILAC-based proteomic profiling of the suppression of TGF-?1-induced lung fibroblast-to-myofibroblast differentiation by trehalose[J]. Toxicology and Applied Pharmacology. 2020, 391: 114916. Liu X, Xie P, Hao N, et al. HIF-1?regulated expression of calreticulin promotes breast tumorigenesis and progression through Wnt/?-catenin pathway activation. Proceedings of the National Academy of Sciences. 2021, 118(44) Cheng X, Qin L, Deng L, et al. SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Non-Small Cell Lung Cancer by Downregulating Epithelial-Mesenchymal Transition via the Wnt/?-Catenin Signaling Pathway. Journal of Cancer. 2021, 12(19): 5825-5837. Gwak J, et al. Cell Res. 2012, 22(1):237-47. Yan Z, Ruan B, Wang S, et al.RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.Archives of Medical Research.2023: 102853.