TargetMol

Carnosol

Product Code:
 
TAR-T6S1302
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S1302-5mg5mg£102.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6S1302-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6S1302-10mg10mg£115.00
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TAR-T6S1302-25mg25mg£161.00
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Quantity:
TAR-T6S1302-50mg50mg£205.00
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TAR-T6S1302-100mg100mg£270.00
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Quantity:
TAR-T6S1302-500mg500mg£563.00
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This product comes from: United States.
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Further Information

Bioactivity:
Carnosol has anti-oxidative, anti-inflammatory, antiproliferative and apoptosis inducing properties. Carnosol enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. 3. Carnosol may as a novel agonist of TRPA1 with an EC5 value of 12.46 μM.
CAS:
5957-80-2
Formula:
C20H26O4
Molecular Weight:
330.424
Pathway:
PI3K/Akt/mTOR signaling; Immunology/Inflammation; Metabolism; MAPK
Purity:
0.99
SMILES:
CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O
Target:
Nrf2; Endogenous Metabolite; S6 Kinase

References

Wei Shi, Guang Xu, Xiaoyan Zhan, Yuan Gao, Zhilei Wang, Shubin Fu, Nan Qin, Xiaorong Hou, Yongqiang Ai, Chunyu Wang, Tingting He, Hongbin Liu, Yuanyuan Chen, Yan Liu, Jiabo Wang, Ming Niu, Yuming Guo, Xiaohe Xiao & Zhaofang Bai Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases. Cell Death & Disease. 2020 Wei Shi, Guang Xu, Xiaoyan Zhan, Yuan Gao, Zhilei Wang, Shubin Fu, Nan Qin, Xiaorong Hou, Yongqiang Ai, Chunyu Wang, Tingting He, Hongbin Liu, Yuanyuan Chen, Yan Liu, Jiabo Wang, Ming Niu, Yuming Guo, Xiaohe Xiao & Zhaofang Bai. Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases. Cell death & disease. 2020 L?pez-Jim?nez, Auxiliadora, Garc?a-Caballero, Melissa, Medina, Miguel ?ngel, et al. Anti-angiogenic properties of carnosol and carnosic acid, two major dietary compounds from rosemary[J]. European Journal of Nutrition, 2013, 52(1):85-95.