TargetMol

WZB117

Product Code:
 
TAR-T7018
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7018-5mg5mg£105.00
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Quantity:
TAR-T7018-1mL1 mL * 10 mM (in DMSO)£109.00
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TAR-T7018-10mg10mg£127.00
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TAR-T7018-25mg25mg£185.00
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TAR-T7018-50mg50mg£259.00
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Quantity:
TAR-T7018-100mg100mg£350.00
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Quantity:
TAR-T7018-200mg200mg£487.00
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Quantity:
TAR-T7018-500mg500mg£739.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
WZB117 is a Glucose Transporter 1 (GLUT1) inhibitor. when IC50 of WZB117 approximate 10 μM, it inhibits lung cancer A549 cells and breast cancer MCF7 cells proliferation.
CAS:
1223397-11-2
Formula:
C20H13FO6
Molecular Weight:
368.316
Pathway:
Metabolism
Purity:
0.9954
SMILES:
Oc1cccc(c1)C(=O)Oc1cccc(F)c1OC(=O)c1cccc(O)c1
Target:
transporter

References

Chen X, Zhao Y, He C, et al. Identification of a novel GLUT1 inhibitor with in vitro and in vivo anti-tumor activity. International Journal of Biological Macromolecules. 2022, 216: 768-778. Liu Y, et al. Mol Cancer Ther. 2012, 11(8):1672-1682. Chen J, Wu D, Dong Z, et al. The expression and role of glycolysis-associated molecules in infantile hemangioma. Life Sciences. 2020, 259: 118215. Chen J, Wu D, Dong Z, et al. The expression and role of glycolysis-associated molecules in infantile hemangioma[J]. Life Sciences. 2020, 259: 118215.